Genesis

Traditional Herbal Medicines (THMs) have been used in the treatment of variety of diseases for thousands of years in India and other Asian Countries because of their natural origin and lesser side effects. However, the safety and efficacy data (in addition to dose and quality parameters) on most of these THMs are far from sufficient to meet the criteria needed to support their world-wide therapeutic use [1,2]. Also, the mechanistic understanding of most of such natural herbal medicines is still lacking [2].  It is assumed that THMs (and so the nutraceuticals) promotes self-healing through establishing and maintaining the homeostasis of organ systems in the body, and interactions with the environment [3]. Fundamentally, the biological activity of any THM is the combined effect of its various constituents that interact with various cellular components (i.e. DNA, RNA, and proteins) to exert synergistic effect.

Kumar Figure 1

Similar to THMs, the scientific evidences of therapeutic efficacy and safety for majority of nutraceutical products and natural medicines is also lacking. Nutraceutical is a hybrid term for ‘nutrition’ and ‘pharmaceutical’ and represents a plant or animal derived product which has its significant role in modifying and maintaining normal physiological function; this in turn helps ameliorating the diseased condition [4]. Recent years have witnessed tremendous growth in the market of nutraceutical products and natural herbal medicines owing to their ability to combat some of the major health problems of the century such as obesity, cardiovascular diseases, respiratory diseases, cancer, osteoporosis, arthritis, diabetes, hypercholesterolemia, etc. [4]. However, it is important to establish the scientific rationale to defend their world-wide therapeutic use in human healthcare managament. Thus, conscience efforts are required to well ensure the efficacy and safety of nutraceutical products, especially those marketed for health-care management of serious human diseases such as cancer. The aim of TBRSI is to promote translational research efforts, especially, in the area of Nutraceuticals and Natural Medicines through promoting collaborations among:

  • OMICS Researchers working in the area of natural products
  • Pre-clinical and Clinical researchers
  • Pharmaceutical and Toxicological Researchers
  • Healthcare Professionals
  • Industrial Professionals
  • Scientists and students from research institutes organizations and universities
  • Pharmaceutical companies, Investors and CEO’s

References:

[1] Web-source: https://nccih.nih.gov/health/ayurveda/introduction.htm

[2] Dinesh Kumar*, Atul Rawat, Durgesh Dubey, Umesh Kumar, Amit K Keshari, Sudipta Saha and Anupam Guleria*, “NMR Based Metabolomics: An Emerging Tool for Therapeutic Evaluation of Traditional Herbal Medicines”. SM-eBOOK: Nuclear Magnetic Resonance Spectroscopy (2016), June, 1-18. Download

[3] Web-source: https://nationaleczema.org/traditional-chinese-medicine-and-eczema/

[4] Das L, Bhaumik E, Raychaudhuri U, Chakraborty R. Role of nutraceuticals in human health. Journal of food science and technology. 2012 Apr 1;49(2):173-83. Online

 

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